No!
The email2 Web Client can be used in conjunction with the email2 Toolbar, but this is not necessary!
Even if you don't use the email2 Toolbar for Outlook, you are able to access the email2 Web Client and retrieve email2 messages addressed to you. This ensures that people that are not using Outlook are not excluded from email2 access.
If you do not have the email2 Toolbar installed, you can access the email2 Web Client by following a link provided for you in the email2 notification message you received via basic e-mail.
The email2 Toolbar allows users to continue to manage all of their e-mails (from different PENs, from basic e-mail servers) in one unified, familiar interface.
The email2 Web Client allows access to extended information regarding specific secure email2 messages.
//Edited June 2009